Hello, I am

Jacob Clarke
I am a fourth-year medical student, and I am passionate about improving patient care through clinical integration with technology.

Education

St. Louis University School of Medicine
MD Candidate

Aug 2018 - Present

      Brigham Young University
      BS of Molecular Biology

      Aug 2013 - Dec 2013, Jan 2016 - Aug 2018

          Publications

          Zhang JK, Patel M, Patel N, Clarke J, Almajali M, Alexopoulos G. Clinical and Radiographic Biomarkers of Delayed Cerebral Ischemia following Aneurysmal Subarachnoid Hemorrhage. Weill Cornell Medicine Neurological Research Symposium, New York City, NY. Jan 2021

          Joshua J. Nelson, Seth R. Stapley, Chris S. Finuf, Elizabeth Anderson, Jacob Clarke, Jordan T. Yorgason, Scott C. Steffensen. Effects of Cocaine on Spontaneous Dopamine Release Varies across Striatal Regions Poster Presented at: Mary-Lou Fulton Conference. 2018 Apr 12; Provo, UT.


          Experiences

          Student Researcher
          St. Louis University School of Medicine

          May 2021 - Present

          • Analyzed the Vaccine Adverse Events Reporting System (VAERS) with AI natural language processing.

          • Created an AI deep learning model to predict vaccine type from symptom text with 82% accuracy (At https://vaers.jacobaclarke.com).

          • Research is ongoing, and I am currently preparing a manuscript submission.

            Saint Louis University School of Medicine

            Oct 2020 - Present

            • Developed software to manage more than 100 weekly volunteer sign-ups at our student-run clinic.

            • This experience showcases my ability to build technical solutions for clinical problems.

            • The clinic leadership created a new "Distinction in Service" award to recognize my unique contributions.

              Survey Developer
              Saint Louis University School of Medicine

              September 2021 - Present

              • After Saint Louis University experienced multiple suicides, I partnered with the Office of Student Affairs to build an early alert system that uses weekly SMS surveys to screen students for depression.

              • Designed the system to provide resources to students and send emergency notifications to faculty when patients are flagged as high risk by the surveys.

                Saint Louis University School of Medicine

                Oct 2020 - Present

                • Built an application to help students understand disease hierarchy by building personal ontology maps of diseases.

                • Piloted with our internal medicine clerkship program with several student cohorts.

                  Research Assistant
                  Brigham Young University

                  Jan 2016 - Jan 2017

                  • Performed immunohistochemical staining, dot blot staining, and gold antibody labeling of cells.

                    Research Assistant
                    Saint Louis University School of Medicine

                    January 2021

                    • Performed statistical analysis on markers for ischemia after subarachnoid hemorrhage.

                      Research Assistant
                      Saint Louis University School of Medicine

                      Jan 2021 - Present

                      • Reported as the first author on a case of pediatric congenital giant megaureter in a 16-year-old female.

                      • My manuscript is currently under review at Urology after the initial request for revisions.

                        Research Assistant
                        Saint Louis University School of Medicine

                        Oct 2020 - Present

                        • Reported on the potential benefits of earlier followup in patients with proliferative AMD after initiation of anti-VEGF therapy.

                        • Our manuscript is currently under review at the Journal of Vitreoretinal Disease.

                          Children's Choir Leader
                          The Church of Jesus Christ of Latter-day Saints

                          June 2019 - Present

                          • Taught weekly lessons for a choir of more than 20 children.

                          • Organized virtual and recorded meetings during the pandemic.

                          • Led two live performances and one virtual performance.

                          • Served families that experienced hardship by tutoring children, visiting their homes, and bringing holiday gifts.

                            Volunteer Pianist
                            Miscelaneous

                            Aug 2018 - Present

                            • Played piano at multiple locations, including [1] a memorial service for anatomy lab body donors, [2] Saint Louis University’s hematology/oncology infusion center, and [3] church services.

                            • The piano is a creative outlet that helps me build resilience.

                              Service Mission
                              The Church of Jesus Christ of Latter-day Saints

                              January 2014 - December 2015

                              • Taught classes about religion and participated in several service projects.

                              • Learned to speak advanced German through daily study and a commitment to speak only German from 9 AM to 9 PM each day.

                              • Hosted English and German courses for immigrants who were seeking work.

                                Research Assistant
                                Saint Louis University School of Medicine

                                Sep 2021 - Present

                                • Under the supervision of the Saint Louis University internal medicine program director, I am designing a resident application ranking system.

                                • I am processing data from ERAS application packets to help identify unique applicants through natural language processing and machine learning.

                                  Student Researcher
                                  Washington University School of Medicine

                                  June 2019 - March 2020

                                  • Published a manuscript about cancer survival disparities by race and geographic location in an AACR journal (Cancer Epidemiology, Biomarkers & Prevention).

                                  • Performed Kaplan Meier and Cox proportional hazard regression analyses using R and Python.

                                  • Having witnessed healthcare disparities in St. Louis, I was proud to advocate for my patients through this research.

                                    Research Assistant
                                    Washington University School of Medicine

                                    Oct 2018 - May 2019

                                    • Established a new immunohistochemical staining protocol.

                                    • Used Python image processing to programmatically identify the number of positive staining cells per sample.

                                    • Evaluator Feedback: "Jacob performed exceptionally well during his research rotation. He used his programming skills to help develop a novel algorithm for data analysis, and independently performed molecular biology experiments essential to our research."

                                      Research Assistant
                                      Brigham Young Steffensen Lab

                                      Aug 2017 - Apr 2018

                                      • Troubleshot a new protocol for isolation of microglia from the mouse brain.

                                      • Trained other students in intracranial viral injections and transcardiac perfusions in rats and mice.

                                      • Performed imaging on mice to check the response of dopamine neuron firing rates to alcohol incubation dose.

                                        Ballet Accompanist
                                        BYU Ballet Department

                                        Dec 2017 - Jun 2018

                                        • Worked as a ballet accompanist, playing for senior-level university courses.

                                        • The ballet classes involved song improvisation and style adaptation; they required a non-repeating repertoire lasting up to five hours.

                                          Mechanic Certification Instructor
                                          Provo Bicycle Collective

                                          Dec 2017 - Jun 2018

                                          • Started as a volunteer by repairing used bikes to donate to the community.

                                          • As an employee, I taught mechanic certification courses at the local juvenile detention center to improve their residents' chances of finding work after release.

                                          • Led multiple volunteer nights at the bicycle shop.

                                            Teaching Assistant
                                            Brigham Young University

                                            Aug 2017 - Dec 2017

                                            • Held weekly office hours to teach students.

                                            • Taught multiple exam reviews.

                                            • Developed a deeper interest in medical education.


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