Hello, I am
Aug 2018 - Present
Aug 2013 - Dec 2013, Jan 2016 - Aug 2018
Wiemken T, Niemotka S, Clarke J, Prener C, Santos Rutchman A. Estimating pediatric cases of COVID-19 over time in the United States: Filling in a gap in public use data. American Journal of Infection Control. in Press.
Zhang JK, Patel M, Patel N, Clarke J, Almajali M, Alexopoulos G. Clinical and Radiographic Biomarkers of Delayed Cerebral Ischemia following Aneurysmal Subarachnoid Hemorrhage. Weill Cornell Medicine Neurological Research Symposium, New York City, NY. Jan 2021
Joshua J. Nelson, Seth R. Stapley, Chris S. Finuf, Elizabeth Anderson, Jacob Clarke, Jordan T. Yorgason, Scott C. Steffensen. Effects of Cocaine on Spontaneous Dopamine Release Varies across Striatal Regions Poster Presented at: Mary-Lou Fulton Conference. 2018 Apr 12; Provo, UT.
May 2021 - Present
Analyzed the Vaccine Adverse Events Reporting System (VAERS) with AI natural language processing.
Created an AI deep learning model to predict vaccine type from symptom text with 82% accuracy (At https://vaers.jacobaclarke.com).
Research is ongoing, and I am currently preparing a manuscript submission.
Jan 2016 - Jan 2017
Performed immunohistochemical staining, dot blot staining, and gold antibody labeling of cells.
Performed statistical analysis on markers for ischemia after subarachnoid hemorrhage.
Jan 2021 - Present
Reported as the first author on a case of pediatric congenital giant megaureter in a 16-year-old female.
My manuscript is currently under review at Urology after the initial request for revisions.
Oct 2020 - Present
Reported on the potential benefits of earlier followup in patients with proliferative AMD after initiation of anti-VEGF therapy.
Our manuscript is currently under review at the Journal of Vitreoretinal Disease.
June 2019 - Present
Taught weekly lessons for a choir of more than 20 children.
Organized virtual and recorded meetings during the pandemic.
Led two live performances and one virtual performance.
Served families that experienced hardship by tutoring children, visiting their homes, and bringing holiday gifts.
Aug 2018 - Present
Played piano at multiple locations, including  a memorial service for anatomy lab body donors,  Saint Louis University’s hematology/oncology infusion center, and  church services.
The piano is a creative outlet that helps me build resilience.
September 2021 - Present
After Saint Louis University experienced multiple suicides, I partnered with the Office of Student Affairs to build an early alert system that uses weekly SMS surveys to screen students for depression.
Designed the system to provide resources to students and send emergency notifications to faculty when patients are flagged as high risk by the surveys.
Oct 2020 - Present
Built an application to help students understand disease hierarchy by building personal ontology maps of diseases.
Piloted with our internal medicine clerkship program with several student cohorts.
January 2014 - December 2015
Taught classes about religion and participated in several service projects.
Learned to speak advanced German through daily study and a commitment to speak only German from 9 AM to 9 PM each day.
Hosted English and German courses for immigrants who were seeking work.
Sep 2021 - Present
Under the supervision of the Saint Louis University internal medicine program director, I am designing a resident application ranking system.
I am processing data from ERAS application packets to help identify unique applicants through natural language processing and machine learning.
June 2019 - March 2020
Published a manuscript about cancer survival disparities by race and geographic location in an AACR journal (Cancer Epidemiology, Biomarkers & Prevention).
Performed Kaplan Meier and Cox proportional hazard regression analyses using R and Python.
Having witnessed healthcare disparities in St. Louis, I was proud to advocate for my patients through this research.
Oct 2020 - Present
Developed software to manage more than 100 weekly volunteer sign-ups at our student-run clinic.
This experience showcases my ability to build technical solutions for clinical problems.
The clinic leadership created a new "Distinction in Service" award to recognize my unique contributions.
Oct 2018 - May 2019
Established a new immunohistochemical staining protocol.
Used Python image processing to programmatically identify the number of positive staining cells per sample.
Evaluator Feedback: "Jacob performed exceptionally well during his research rotation. He used his programming skills to help develop a novel algorithm for data analysis, and independently performed molecular biology experiments essential to our research."
Aug 2017 - Apr 2018
Troubleshot a new protocol for isolation of microglia from the mouse brain.
Trained other students in intracranial viral injections and transcardiac perfusions in rats and mice.
Performed imaging on mice to check the response of dopamine neuron firing rates to alcohol incubation dose.
Dec 2018 - Jun 2018
Worked as a ballet accompanist, playing for senior-level university courses.
The ballet classes involved song improvisation and style adaptation; they required a non-repeating repertoire lasting up to five hours.
Dec 2017 - Jun 2018
Started as a volunteer by repairing used bikes to donate to the community.
As an employee, I taught mechanic certification courses at the local juvenile detention center to improve their residents' chances of finding work after release.
Led multiple volunteer nights at the bicycle shop.
Aug 2017 - Dec 2017
Held weekly office hours to teach students.
Taught multiple exam reviews.
Developed a deeper interest in medical education.